Application Detail
Description of Medical Service
Measurement of NT-proBNP (also known as N-terminal pro-brain natriuretic peptide, N-terminal pro-B-type natriuretic peptide or N-terminal prohormone of brain natriuretic peptide) through a blood test. The blood test is intended to enable the early detection of systemic sclerosis related pulmonary arterial hypertension, and be used as a regular assessment of pulmonary arterial hypertension disease progression.Description of Medical Condition
Pulmonary arterial hypertension is characterised by increased pulmonary vascular resistance (resistance against blood flow), and may be idiopathic (arising from an unknown cause), or due to other underlying factors or disease associations such as connective tissue disease.Reason for Application
At the July 2022 meeting, MSAC considered an application requesting Medicare Benefits Schedule (MBS) listing of N-terminal pro B-type natriuretic peptide (NT-proBNP) biomarker assay for (1) detection of pulmonary arterial hypertension (PAH) in patients with systemic sclerosis (SSc), and for (2) risk assessment of patients diagnosed with PAH. After consideration, MSAC supported the creation of a new MBS item for the quantification of laboratory-based NT-proBNP testing for detection of PAH in patients with SSc, but did not support public funding for NT-proBNP testing in patients with an established diagnosis of PAH. Application 1689.1 is a reapplication that aims to address the concerns of MSAC and requests MBS listing for NT-proBNP testing in patients with an established diagnosis of PAH.Medical Service Type
Investigative technologyPrevious Application Number/s
1689Associated Documentation
Application Summary
An updated application has been received for this resubmission, and a summary of the application is as followsApplication Summary (PDF 527 KB)
Application Summary (Word 53 KB)
Consultation Survey
Consultation Survey (PDF 656 KB)Consultation Survey (Word 27 KB)
PASC Consultation
Bypassing PASC
MSAC Consultation
MSAC consultation input closed Friday, 9 June 2023.
For further information please refer to PASC, ESC, MSAC Key Dates
For further information on the consultation process please refer to MSAC Consultation Process
PICO Confirmation
Not applicableAssessment Report
-Public Summary Document
Public Summary Document (PDF 887 KB)Public Summary Document (Word 570 KB)